Xenotransplantation of Mitochondrial Electron Transfer Enzyme, Ndi1, in Myocardial Reperfusion Injury

A significant consequence of ischemia/reperfusion (I/R) is mitochondrial respiratory dysfunction, leading to energetic deficits and cellular toxicity from reactive oxygen species (ROS). Mammalian complex I, a NADH-quinone oxidoreductase enzyme, is a multiple subunit enzyme that oxidizes NADH and pum...

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Bibliografiske detaljer
Main Authors: Perry, Cynthia N., Huang, Chengqun, Liu, Wayne, Magee, Najib, Sousa Carreira, Raquel, Gottlieb, Roberta A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038860/
https://ncbi.nlm.nih.gov/pubmed/21339825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016288
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