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Unexpected protective role for Toll-like receptor 3 in the arterial wall

The critical role of Toll-like receptors (TLRs) in mammalian host defense has been extensively explored in recent years. The capacity of about 10 TLRs to recognize conserved patterns on many bacterial and viral pathogens is remarkable. With so few receptors, cross-reactivity with self-tissue compone...

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Autores principales: Cole, Jennifer E., Navin, Tina J., Cross, Amanda J., Goddard, Michael E., Alexopoulou, Lena, Mitra, Anuja T., Davies, Alun H., Flavell, Richard A., Feldmann, Marc, Monaco, Claudia
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038746/
https://ncbi.nlm.nih.gov/pubmed/21220319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018515108
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