Unexpected protective role for Toll-like receptor 3 in the arterial wall

The critical role of Toll-like receptors (TLRs) in mammalian host defense has been extensively explored in recent years. The capacity of about 10 TLRs to recognize conserved patterns on many bacterial and viral pathogens is remarkable. With so few receptors, cross-reactivity with self-tissue compone...

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Bibliographic Details
Main Authors: Cole, Jennifer E., Navin, Tina J., Cross, Amanda J., Goddard, Michael E., Alexopoulou, Lena, Mitra, Anuja T., Davies, Alun H., Flavell, Richard A., Feldmann, Marc, Monaco, Claudia
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2011
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038746/
https://ncbi.nlm.nih.gov/pubmed/21220319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018515108
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