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Molecular basis for ubiquitin and ISG15 cross-reactivity in viral ovarian tumor domains

Crimean Congo hemorrhagic fever virus (CCHFV) is a deadly human pathogen that evades innate immune responses by efficiently interfering with antiviral signaling pathways mediated by NF-κB, IRF3, and IFNα/β. These pathways rely on protein ubiquitination for their activation, and one outcome is the mo...

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Bibliografiske detaljer
Main Authors: Akutsu, Masato, Ye, Yu, Virdee, Satpal, Chin, Jason W., Komander, David
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038727/
https://ncbi.nlm.nih.gov/pubmed/21266548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1015287108
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