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Computational design of the lasso peptide antibiotic microcin J25
Microcin J25 (MccJ25) is a 21 amino acid (aa) ribosomally synthesized antimicrobial peptide with an unusual structure in which the eight N-terminal residues form a covalently cyclized macrolactam ring through which the remaining 13 aa tail is fed. An open question is the extent of sequence space tha...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3038460/ https://ncbi.nlm.nih.gov/pubmed/21106549 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzq108 |
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