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Computational design of the lasso peptide antibiotic microcin J25

Microcin J25 (MccJ25) is a 21 amino acid (aa) ribosomally synthesized antimicrobial peptide with an unusual structure in which the eight N-terminal residues form a covalently cyclized macrolactam ring through which the remaining 13 aa tail is fed. An open question is the extent of sequence space tha...

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Bibliografische gegevens
Hoofdauteurs: Pan, Si Jia, Cheung, Wai Ling, Fung, Ho Ki, Floudas, Christodoulos A., Link, A. James
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038460/
https://ncbi.nlm.nih.gov/pubmed/21106549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzq108
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