Ablation of human colon carcinoma in nude mice by 131I-labeled monoclonal anti-carcinoembryonic antigen antibody F(ab')2 fragments.

Pooled F(ab')2 fragments of three MAbs against distinct epitopes of carcinoembryonic antigen (CEA) were used for radioimmunotherapy of nude mice bearing a subcutaneous human colon carcinoma xenograft. 9-10 d after transplantation when tumor nodules were in exponential growth, 36 mice were treated by...

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Bibliografiske detaljer

Udgivet i:	J Clin Invest
Principais autores:	Buchegger, F, Pfister, C, Fournier, K, Prevel, F, Schreyer, M, Carrel, S, Mach, J P
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Clinical Investigation 1989
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303846/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2708519/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114037
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