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Ablation of human colon carcinoma in nude mice by 131I-labeled monoclonal anti-carcinoembryonic antigen antibody F(ab')2 fragments.

Pooled F(ab')2 fragments of three MAbs against distinct epitopes of carcinoembryonic antigen (CEA) were used for radioimmunotherapy of nude mice bearing a subcutaneous human colon carcinoma xenograft. 9-10 d after transplantation when tumor nodules were in exponential growth, 36 mice were treated by...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Buchegger, F, Pfister, C, Fournier, K, Prevel, F, Schreyer, M, Carrel, S, Mach, J P
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303846/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2708519/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114037
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