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Total Synthesis of (+)-Nankakurines A and B and (±)-5-epi-Nankakurine A

The first total syntheses of the Lycopodium alkaloids (+)-nankakurine A (2), (+)-nankakurine B (3) and the originally purported structure 1 of nankakurine A were accomplished. The syntheses of 2 and 3 feature a demanding intramolecular azomethine imine cycloaddition as the key step for generating th...

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Bibliographic Details
Main Authors: Altman, Ryan A., Nilsson, Bradley L., Overman, Larry E., de Alaniz, Javier Read, Rohde, Jason M., Taupin, Veronique
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038189/
https://ncbi.nlm.nih.gov/pubmed/20958075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo101619d
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