Principal Component Analysis Reveals Age-Related and Muscle-Type-Related Differences in Protein Carbonyl Profiles of Muscle Mitochondria

Carbonyl-modified proteins are considered markers of oxidative damage caused by oxidative stress, aging, and disease. Here we use a previously developed capillary electrophoretic method for detecting femtomole (10(−15) mole) carbonyl levels in mitochondrial proteins that are size separated and profi...

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Main Authors: Feng, Juan, Navratil, Marian, Thompson, LaDora V., Arriaga, Edgar A.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038117/
https://ncbi.nlm.nih.gov/pubmed/19126840
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