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Semi-automated image analysis: detecting carbonylation in subcellular regions of skeletal muscle

The level of carbonylation in skeletal muscle is a marker of oxidative damage associated with disease and aging. While immunofluorescence microscopy is an elegant method to identify carbonylation sites in muscle cross-sections, imaging analysis is manual, tedious, and time consuming, especially when...

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Detalhes bibliográficos
Main Authors: Kostal, Vratislav, Levar, Kiara, Swift, Mark, Skillrud, Erik, Chapman, Mark, Thompson, LaDora V., Arriaga, Edgar A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3066023/
https://ncbi.nlm.nih.gov/pubmed/21327623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-011-4725-9
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