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Immune interferon inhibits proliferation and induces 2'-5'-oligoadenylate synthetase gene expression in human vascular smooth muscle cells.

Proliferation of vascular smooth muscle cells (SMC) contributes to formation of the complicated human atherosclerotic plaque. These lesions also contain macrophages, known to secrete SMC mitogens, and T lymphocytes. Many of the SMC in the lesions express class II major histocompatibility antigens, a...

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Udgivet i:J Clin Invest
Principais autores: Warner, S J, Friedman, G B, Libby, P
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1989
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303804/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2495301/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113998
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