XOMA 052, a potent, high-affinity monoclonal antibody for the treatment of IL-1β-mediated diseases

Interleukin-1β (IL-1β) is a potent mediator of inflammatory responses and plays a role in the differentiation of a number of lymphoid cells. In several inflammatory and autoimmune diseases, serum levels of IL-1β are elevated and correlate with disease development and severity. The central role of th...

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Détails bibliographiques
Auteurs principaux: Owyang, Alexander M, Issafras, Hassan, Corbin, John, Ahluwalia, Kiran, Larsen, Paul, Pongo, Elizabeth, Handa, Masahisa, Horwitz, Arnold H, Roell, Marina K, Haak-Frendscho, Mary, Masat, Linda
Format: Artigo
Langue:Inglês
Publié: Landes Bioscience 2011
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038011/
https://ncbi.nlm.nih.gov/pubmed/21048425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.3.1.13989
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