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The Accumulation of Intracellular ITEGE and DIPEN Neoepitopes in Bovine Articular Chondrocytes Is Mediated by CD44 Internalization of Hyaluronan

OBJECTIVE: A dramatic loss of aggrecan proteoglycan from cartilage is associated with osteoarthritis. The fate of residual G1 domains of aggrecan is unknown, but inefficient turnover of these domains may impede subsequent repair and retention of newly synthesized aggrecan. Thus, the objective of thi...

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Main Authors: Flory, Jennifer J. Embry, Fosang, Amanda J., Knudson, Warren
Format: Artigo
Sprog:Inglês
Udgivet: 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3037829/
https://ncbi.nlm.nih.gov/pubmed/16447219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.21623
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