Bacterial lipopolysaccharides prime human neutrophils for enhanced production of leukotriene B4.

Neutrophils can be "primed" for an enhanced respiratory burst by lipopolysaccharide (LPS) in concentrations measurable in patients with septic shock. Leukotriene B4 (LTB4) is the primary eicosanoid product of neutrophils and is felt to be a mediator of host defense and inflammation. We investigated...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Doerfler, M E, Danner, R L, Shelhamer, J H, Parrillo, J E
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1989
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303773/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2537852/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113983
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