Bacterial lipopolysaccharides prime human neutrophils for enhanced production of leukotriene B4.

Neutrophils can be "primed" for an enhanced respiratory burst by lipopolysaccharide (LPS) in concentrations measurable in patients with septic shock. Leukotriene B4 (LTB4) is the primary eicosanoid product of neutrophils and is felt to be a mediator of host defense and inflammation. We investigated...

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Vydáno v:	J Clin Invest
Hlavní autoři:	Doerfler, M E, Danner, R L, Shelhamer, J H, Parrillo, J E
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Clinical Investigation 1989
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303773/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2537852/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113983
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