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Activity of BK(Ca) Channel Is Modulated by Membrane Cholesterol Content and Association with Na(+)/K(+)-ATPase in Human Melanoma IGR39 Cells
Interaction of large conductance Ca(2+)- and voltage-activated K(+) (BK(Ca)) channels with Na(+)/K(+)-ATPase, caveolin-1, and cholesterol was studied in human melanoma IGR39 cells. Functional BK(Ca) channels were enriched in caveolin-rich and detergent-resistant membranes, i.e. rafts, and blocking o...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3037676/ https://ncbi.nlm.nih.gov/pubmed/21135099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.149898 |
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