Functional Diversity of Heat-labile Toxins (LT) Produced by Enterotoxigenic Escherichia coli: DIFFERENTIAL ENZYMATIC AND IMMUNOLOGICAL ACTIVITIES OF LT1 (hLT) AND LT4 (pLT)

Heat-labile toxins (LTs) have ADP-ribosylation activity and induce the secretory diarrhea caused by enterotoxigenic Escherichia coli (ETEC) strains in different mammalian hosts. LTs also act as adjuvants following delivery via mucosal, parenteral, or transcutaneous routes. Previously we have shown t...

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Bibliographic Details
Main Authors: Rodrigues, Juliana F., Mathias-Santos, Camila, Sbrogio-Almeida, Maria Elisabete, Amorim, Jaime H., Cabrera-Crespo, Joaquim, Balan, Andrea, Ferreira, Luís C. S.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Microbiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3037635/
https://ncbi.nlm.nih.gov/pubmed/21135101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.173682
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