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Prodomains of Transforming Growth Factor β (TGFβ) Superfamily Members Specify Different Functions: EXTRACELLULAR MATRIX INTERACTIONS AND GROWTH FACTOR BIOAVAILABILITY

The specific functions of the prodomains of TGFβ superfamily members are largely unknown. Interactions are known between prodomains of TGFβ-1–3 and latent TGFβ-binding proteins and between prodomains of BMP-2, -4, -7, and -10 and GDF-5 and fibrillins, raising the possibility that latent TGFβ-binding...

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Detalles Bibliográficos
Main Authors: Sengle, Gerhard, Ono, Robert N., Sasaki, Takako, Sakai, Lynn Y.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3037620/
https://ncbi.nlm.nih.gov/pubmed/21135108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.188615
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