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A New Model for Growth Factor Activation: Type II Receptors Compete with the Prodomain for BMP-7
Bone morphogenetic proteins (BMPs) are morphogens with long-range signaling activities. BMP-7 is secreted as a stable complex consisting of a growth factor noncovalently associated with two propeptides. In other transforming growth factor-β-like growth factor complexes, the prodomain (pd) confers la...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2705212/ https://ncbi.nlm.nih.gov/pubmed/18621057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.06.074 |
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