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Neuroprotection by Minocycline Caused by Direct and Specific Scavenging of Peroxynitrite
Minocycline prevents oxidative protein modifications and damage in disease models associated with inflammatory glial activation and oxidative stress. Although the drug has been assumed to act by preventing the up-regulation of proinflammatory enzymes, we probed here its direct chemical interaction w...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3037611/ https://ncbi.nlm.nih.gov/pubmed/21081502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.169565 |
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