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Cy3-DNA Stacking Interactions Strongly Depend on the Identity of the Terminal Basepair
We characterized the effect of the first basepair on the conformational dynamics of the fluorescent dye Cy3 attached to the 5′ end of double-stranded DNA using Gaussian-mixture adaptive umbrella sampling simulations. In the simulations, the sampling of all five dihedral angles along the linker was e...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Biophysical Society
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3037574/ https://ncbi.nlm.nih.gov/pubmed/21320450 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.01.014 |
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