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Transportin 3 and importin α are required for effective nuclear import of HIV-1 integrase in virus-infected cells

Unlike other retroviruses, human immunodeficiency virus type-1 (HIV-1) can infect terminally differentiated cells, due to the ability of its pre-integration complex (PIC) to translocate via the host nuclear pore complex (NPC). The PIC Nuclear import has been suggested to be mediated by the viral int...

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Autors principals: Levin, Aviad, Hayouka, Zvi, Friedler, Assaf, Loyter, Abraham
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3037538/
https://ncbi.nlm.nih.gov/pubmed/21326825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.1.5.12903
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