Interleukin-10 repletion suppresses pro-inflammatory cytokines and decreases liver pathology without altering viral replication in murine cytomegalovirus (MCMV)-infected IL-10 knockout mice

OBJECTIVE AND DESIGN: To determine the role of interleukin-10 (IL-10) in protecting against the deleterious pro-inflammatory cytokine response to murine cytomegalovirus (MCMV), we studied the impact of IL-10 repletion in MCMV-infected IL-10 knockout (KO) mice. MATERIALS AND METHODS: IL-10 KO mice we...

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Detalhes bibliográficos
Main Authors: Tang-Feldman, Yajarayma J., Lochhead, G. Raymond, Lochhead, Stephanie R., Yu, Cindy, Pomeroy, Claire
Formato: Artigo
Idioma:Inglês
Publicado em: SP Birkhäuser Verlag Basel 2010
Assuntos:
Original Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3036806/
https://ncbi.nlm.nih.gov/pubmed/20922456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00011-010-0259-4
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