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The utility of geometrical and chemical restraint information extracted from predicted ligand binding sites in protein structure refinement

Exhaustive exploration of molecular interactions at the level of complete proteomes requires efficient and reliable computational approaches to protein function inference. Ligand docking and ranking techniques show considerable promise in their ability to quantify the interactions between proteins a...

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Detalles Bibliográficos
Main Authors: Brylinski, Michal, Lee, Seung Yup, Zhou, Hongyi, Skolnick, Jeffrey
Formato: Artigo
Idioma:Inglês
Publicado: 2010
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3036769/
https://ncbi.nlm.nih.gov/pubmed/20850544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2010.09.009
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