The Varicella-Zoster Virus ORF47 Kinase Interferes with Host Innate Immune Response by Inhibiting the Activation of IRF3

The innate immune response constitutes the first line of host defence that limits viral spread and plays an important role in the activation of adaptive immune response. Viral components are recognized by specific host pathogen recognition receptors triggering the activation of IRF3. IRF3, along wit...

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Autori principali: Vandevenne, Patricia, Lebrun, Marielle, El Mjiyad, Nadia, Ote, Isabelle, Di Valentin, Emmanuel, Habraken, Yvette, Dortu, Estelle, Piette, Jacques, Sadzot-Delvaux, Catherine
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3036730/
https://ncbi.nlm.nih.gov/pubmed/21347389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016870
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