The Varicella-Zoster Virus ORF47 Kinase Interferes with Host Innate Immune Response by Inhibiting the Activation of IRF3

The innate immune response constitutes the first line of host defence that limits viral spread and plays an important role in the activation of adaptive immune response. Viral components are recognized by specific host pathogen recognition receptors triggering the activation of IRF3. IRF3, along wit...

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Main Authors: Vandevenne, Patricia, Lebrun, Marielle, El Mjiyad, Nadia, Ote, Isabelle, Di Valentin, Emmanuel, Habraken, Yvette, Dortu, Estelle, Piette, Jacques, Sadzot-Delvaux, Catherine
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3036730/
https://ncbi.nlm.nih.gov/pubmed/21347389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016870
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