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Large Induces Functional Glycans in an O-Mannosylation Dependent Manner and Targets GlcNAc Terminals on Alpha-Dystroglycan

Alpha-dystroglycan (α-DG) is a ubiquitously expressed receptor for extracellular matrix proteins and some viruses, and plays a pivotal role in a number of pathological events, including cancer progression, muscular dystrophies, and viral infection. The O-glycans on α-DG are essential for its ligand...

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מידע ביבליוגרפי
Main Authors: Hu, Yihong, Li, Zhi-fang, Wu, Xiaohua, Lu, Qilong
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3036717/
https://ncbi.nlm.nih.gov/pubmed/21347376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016866
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