Muscle cell differentiation is associated with increased insulin receptor biosynthesis and messenger RNA levels.

Muscle is a major tissue for insulin action. To study the effect of muscle differentiation on insulin receptors, we employed cultured mouse muscle BC3H-1 and C2 cells. In both cell lines differentiation from myoblasts to myocytes was associated with a 5-10-fold increase in specific 125I-insulin bind...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Brunetti, A, Maddux, B A, Wong, K Y, Goldfine, I D
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1989
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303661/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2910907/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113858
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