Muscle cell differentiation is associated with increased insulin receptor biosynthesis and messenger RNA levels.
Muscle is a major tissue for insulin action. To study the effect of muscle differentiation on insulin receptors, we employed cultured mouse muscle BC3H-1 and C2 cells. In both cell lines differentiation from myoblasts to myocytes was associated with a 5-10-fold increase in specific 125I-insulin bind...
Guardat en:
| Publicat a: | J Clin Invest |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Clinical Investigation
1989
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303661/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2910907/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113858 |
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