Fine Mapping of Genetic Variants in BIN1, CLU, CR1 and PICALM for Association with Cerebrospinal Fluid Biomarkers for Alzheimer's Disease

Recent genome-wide association studies of Alzheimer's disease (AD) have identified variants in BIN1, CLU, CR1 and PICALM that show replicable association with risk for disease. We have thoroughly sampled common variation in these genes, genotyping 355 variants in over 600 individuals for whom m...

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Главные авторы: Kauwe, John S. K., Cruchaga, Carlos, Karch, Celeste M., Sadler, Brooke, Lee, Mo, Mayo, Kevin, Latu, Wayne, Su'a, Manti, Fagan, Anne M., Holtzman, David M., Morris, John C., Goate, Alison M.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2011
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3036586/
https://ncbi.nlm.nih.gov/pubmed/21347408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015918
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