Histone deacetylase inhibitors sodium butyrate and valproic acid delay spontaneous cell death in purified rat retinal ganglion cells

PURPOSE: Histone deacetylase inhibitors (HDACi) have neuroprotective effects under various neurodegenerative conditions, e.g., after optic nerve crush (ONC). HDACi-mediated protection of central neurons by increased histone acetylation has not previously been demonstrated in rat retinal ganglion cel...

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Bibliografiska uppgifter
Huvudupphovsmän: Biermann, Julia, Boyle, Jennifer, Pielen, Amelie, Lagrèze, Wolf Alexander
Materialtyp: Artigo
Språk:Inglês
Publicerad: Molecular Vision 2011
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3036563/
https://ncbi.nlm.nih.gov/pubmed/21311741
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