Reciprocal regulation of antral gastrin and somatostatin gene expression by omeprazole-induced achlorhydria.
Gastric acid exerts a feedback inhibition on the secretion of gastrin from antral G cells. This study examines whether gastrin gene expression is also regulated by changes in gastric pH. Achlorhydria was induced in rats by the gastric H+/K+ ATPase inhibitor, omeprazole (100 mumol/kg). This resulted...
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| Udgivet i: | J Clin Invest |
|---|---|
| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
1988
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303620/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2901431/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113662 |
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