Reciprocal regulation of antral gastrin and somatostatin gene expression by omeprazole-induced achlorhydria.

Gastric acid exerts a feedback inhibition on the secretion of gastrin from antral G cells. This study examines whether gastrin gene expression is also regulated by changes in gastric pH. Achlorhydria was induced in rats by the gastric H+/K+ ATPase inhibitor, omeprazole (100 mumol/kg). This resulted...

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Pubblicato in:	J Clin Invest
Autori principali:	Brand, S J, Stone, D
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1988
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303620/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2901431/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113662
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