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Oxidant-induced DNA damage of target cells.

In this study we examined the leukocytic oxidant species that induce oxidant damage of DNA in whole cells. H2O2 added extracellularly in micromolar concentrations (10-100 microM) induced DNA strand breaks in various target cells. The sensitivity of a specific target cell was inversely correlated to...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Schraufstätter, I, Hyslop, P A, Jackson, J H, Cochrane, C G
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1988
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303618/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2843565/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113660
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