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Oxidant-induced DNA damage of target cells.

In this study we examined the leukocytic oxidant species that induce oxidant damage of DNA in whole cells. H2O2 added extracellularly in micromolar concentrations (10-100 microM) induced DNA strand breaks in various target cells. The sensitivity of a specific target cell was inversely correlated to...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Schraufstätter, I, Hyslop, P A, Jackson, J H, Cochrane, C G
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303618/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2843565/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113660
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