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Acidosis during early reperfusion prevents myocardial stunning in perfused ferret hearts.

Cellular calcium overload figures prominently in the pathogenesis of the contractile dysfunction observed after brief periods of ischemia (myocardial stunning). Because acidosis is known to antagonize Ca influx and the intracellular binding of Ca, we reasoned that acidosis during reperfusion might p...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Kitakaze, M, Weisfeldt, M L, Marban, E
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303603/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3417873/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113699
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