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Acidosis during early reperfusion prevents myocardial stunning in perfused ferret hearts.

Cellular calcium overload figures prominently in the pathogenesis of the contractile dysfunction observed after brief periods of ischemia (myocardial stunning). Because acidosis is known to antagonize Ca influx and the intracellular binding of Ca, we reasoned that acidosis during reperfusion might p...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Kitakaze, M, Weisfeldt, M L, Marban, E
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1988
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303603/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3417873/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113699
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