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Asf1/HIRA facilitate global histone deacetylation and associate with HP1 to promote nucleosome occupancy at heterochromatic loci

Heterochromatin impacts various nuclear processes by providing a recruiting platform for diverse chromosomal proteins. In fission yeast, HP1 proteins Chp2 and Swi6, which bind to methylated histone H3 lysine 9, associate with SHREC (Snf2/HDAC repressor complex) and Clr6 histone deacetylases (HDACs)...

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Detalhes bibliográficos
Main Authors: Yamane, Kenichi, Mizuguchi, Takeshi, Cui, Bowen, Zofall, Martin, Noma, Ken-ichi, Grewal, Shiv I. S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035992/
https://ncbi.nlm.nih.gov/pubmed/21211723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.12.009
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