A Novel jmjC Domain Protein Modulates Heterochromatization in Fission Yeast

The heterochromatin domain at the mat locus of Schizosaccharomyces pombe is bounded by the IR-L and IR-R barriers. A genetic screen for mutations that promote silencing beyond IR-L revealed a novel gene named epe1, encoding a conserved nuclear protein with a jmjC domain. Disruption of epe1 promotes...

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Autors principals: Ayoub, Nabieh, Noma, Ken-ichi, Isaac, Sara, Kahan, Tamar, Grewal, Shiv I. S., Cohen, Amikam
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
Matèries:
DNA Dynamics and Chromosome Structure
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC156127/
https://ncbi.nlm.nih.gov/pubmed/12773576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.12.4356-4370.2003
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