IDH1 and IDH2 mutation studies in 1473 patients with chronic-, fibrotic- or blast-phase essential thrombocythemia, polycythemia vera or myelofibrosis

In a multi-institutional collaborative project, 1473 patients with myeloproliferative neoplasms (MPN) were screened for isocitrate dehydrogenase 1 (IDH1)/IDH2 mutations: 594 essential thrombocythemia (ET), 421 polycythemia vera (PV), 312 primary myelofibrosis (PMF), 95 post-PV/ET MF and 51 blast-pha...

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Hauptverfasser: Tefferi, A, Lasho, T L, Abdel-Wahab, O, Guglielmelli, P, Patel, J, Caramazza, D, Pieri, L, Finke, C M, Kilpivaara, O, Wadleigh, M, Mai, M, McClure, R F, Gilliland, D G, Levine, R L, Pardanani, A, Vannucchi, A M
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2010
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035975/
https://ncbi.nlm.nih.gov/pubmed/20508616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2010.113
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