Palmitoylation of human FasL modulates its cell death-inducing function

Fas ligand (FasL) is a transmembrane protein that regulates cell death in Fas-bearing cells. FasL-mediated cell death is essential for immune system homeostasis and the elimination of viral or transformed cells. Because of its potent cytotoxic activity, FasL expression at the cell surface is tightly...

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Detalhes bibliográficos
Main Authors: Guardiola-Serrano, F, Rossin, A, Cahuzac, N, Lückerath, K, Melzer, I, Mailfert, S, Marguet, D, Zörnig, M, Hueber, A-O
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035908/
https://ncbi.nlm.nih.gov/pubmed/21368861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2010.62
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