Apoptosis-inducing factor deficiency decreases the proliferation rate and protects the subventricular zone against ionizing radiation

Cranial radiotherapy in children often leads to progressive cognitive decline. We have established a rodent model of irradiation-induced injury to the young brain. A single dose of 8 Gy was administered to the left hemisphere of postnatal day 10 (P10) mice. Harlequin (Hq) mice, carrying the hypomorp...

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Detalhes bibliográficos
Main Authors: Osato, K, Sato, Y, Ochiishi, T, Osato, A, Zhu, C, Sato, M, Swanpalmer, J, Modjtahedi, N, Kroemer, G, Kuhn, H G, Blomgren, K
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035904/
https://ncbi.nlm.nih.gov/pubmed/21368857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2010.63
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