Inhibition of NF-κB activation sensitizes U937 cells to 3′-azido-3′-deoxythymidine induced apoptosis

In this study, we investigated molecular mechanisms underlying low susceptibility to apoptosis induced by the nucleoside analog azidothymidine (AZT) and the role of nuclear factor-κB (NF-κB) activation in these phenomena. A preliminary screening in different cell lines indicated U937 monocytic cell...

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Detalhes bibliográficos
Main Authors: Matteucci, C, Minutolo, A, Balestrieri, E, Marino-Merlo, F, Bramanti, P, Garaci, E, Macchi, B, Mastino, A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035897/
https://ncbi.nlm.nih.gov/pubmed/21368854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2010.58
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