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A Thermodynamic Approach to the Mechanism of Cell-Penetrating Peptides in Model Membranes

We report a first test of the hypothesis that the mechanism of antimicrobial, cytolytic, and amphipathic cell-penetrating peptides in model membranes is determined by the thermodynamics of peptide insertion into the lipid bilayer from the surface-associated state. Three peptides were designed with m...

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Autors principals: McKeown, Alesia N., Naro, Jeffrey L., Huskins, Laura J., Almeida, Paulo F.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035854/
https://ncbi.nlm.nih.gov/pubmed/21166473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1013358
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