Buprenorphine Reduces Alcohol Drinking Through Activation of the Nociceptin/Orphanin FQ-NOP Receptor System

BACKGROUND: Activation of the NOP receptor by its endogenous ligand nociceptin/orphanin FQ reduces ethanol intake in genetically selected alcohol preferring Marchigian Sardinian alcohol preferring (msP) rats. Here we evaluated whether buprenorphine, a partial agonist at μ-opioid and NOP receptors, w...

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Hlavní autoři: Ciccocioppo, Roberto, Economidou, Daina, Rimondini, Roberto, Sommer, Wolfgang, Massi, Maurizio, Heilig, Markus
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035814/
https://ncbi.nlm.nih.gov/pubmed/16533497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2006.01.006
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