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Attenuation of ethanol self-administration and of conditioned reinstatement of alcohol-seeking behaviour by the antiopioid peptide nociceptin/orphanin FQ in alcohol-preferring rats

RATIONALE: Nociceptin/orphanin FQ (N/OFQ), the endogenous ligand of the opioid-like orphan receptor NOP, was shown to reduce home-cage ethanol consumption, ethanol-induced conditioned place preference and stress-induced reinstatement of alcohol-seeking behaviour. OBJECTIVES: The present study, using...

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Bibliografische gegevens
Hoofdauteurs: Ciccocioppo, Roberto, Economidou, Daina, Fedeli, Amalia, Angeletti, Stefania, Weiss, Friedbert, Heilig, Markus, Massi, Maurizio
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2003
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035816/
https://ncbi.nlm.nih.gov/pubmed/14624331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-003-1645-1
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