Role of Innate Immunity in a Model of Histidyl-tRNA Synthetase (Jo-1)-mediated Myositis

OBJECTIVES: Previous work in humans and in animal models supports a key role for histidyl-tRNA synthetase (HRS=Jo-1) in the pathogenesis of idiopathic inflammatory myopathy. While most investigations have focused on the ability of HRS to trigger adaptive immune responses, in vitro studies clearly in...

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Huvudupphovsmän: Soejima, Makoto, Kang, Eun Ha, Gu, Xinyan, Katsumata, Yasuhiro, Clemens, Paula R., Ascherman, Dana P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035731/
https://ncbi.nlm.nih.gov/pubmed/21280002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.30113
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