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Sequence conservation of apolipoprotein A-I affords novel insights into HDL structure-function

We performed alignment of apolipoprotein A-I (apoA-I) sequences from 31 species of animals. We found there is specific conservation of salt bridge-forming residues in the first 30 residues of apoA-I and general conservation of a variety of residue types in the central domain, helix 2/3 to helix 7/8....

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Autores principales: Bashtovyy, Denys, Jones, Martin K., Anantharamaiah, G. M., Segrest, Jere P.
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Biochemistry and Molecular Biology 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035680/
https://ncbi.nlm.nih.gov/pubmed/21159667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.R012658
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