Specific Age-Associated DNA Methylation Changes in Human Dermal Fibroblasts

Epigenetic modifications of cytosine residues in the DNA play a critical role for cellular differentiation and potentially also for aging. In mesenchymal stromal cells (MSC) from human bone marrow we have previously demonstrated age-associated methylation changes at specific CpG-sites of development...

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Main Authors: Koch, Carmen M., Suschek, Christoph V., Lin, Qiong, Bork, Simone, Goergens, Maria, Joussen, Sylvia, Pallua, Norbert, Ho, Anthony D., Zenke, Martin, Wagner, Wolfgang
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035656/
https://ncbi.nlm.nih.gov/pubmed/21347436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016679
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